Clinical Biomarker Leader/Translational Scientist, Associate Director - Leiden (NL), Basel (CH) or Mechelen (BE)

Pleased to meet you, we are Galapagos, a dynamic growing Biotech company with offices across Europe and in US, headquartered in Mechelen, Belgium.

We are in the business of changing lives. Focusing on high unmet medical needs, we synergize compelling science, technology, and collaborative approaches to create a deep pipeline of best-in-class small molecules, CAR-T therapies and biologics in oncology and immunology. With capabilities from lab to patient, including a decentralized, point-of-care CAR-T manufacturing network, we are committed to challenging the status quo and delivering results for our patients, employees and shareholders.

We pioneer for patients. We need thought leaders and rapid thinkers, entrepreneurs in spirit and status quo-fighters. Collaborative innovators and perseverant idealists. We need the best-in-class. In other words, we need you : The ‘make-it-happener’.

We are looking for a Clinical Biomarker Leader/Translational Scientist, Manager to join our team in Basel (Switzerland) or Leiden (The Netherlands).

Scope of the job

As a Clinical Biomarker Leader / Translational Scientist you join Galapagos’ Translational Science team in the Leiden Bio Science Park. You play a key role in the design, analysis, interpretation and reporting of product characterization and immune monitoring data. Furthermore, you will be establishing internal and external assays including PK/PD/immunogenicity for CAR-T cell clinical trials with internal AD/QC team as well as CROs. You enjoy working in close collaboration with Clinical Development, Process Development, Analytical Development and other stakeholders to ensure relevant data are collected.

As an experienced professional with a complete understanding of the field of translational research you will become instrumental in the development of our clinical programs with novel CAR-T therapies in multiple (hemato-)oncological or immunological indications towards clinical trials and regulatory approval. By doing so, you contribute directly to the treatment of patients, and the generation of data to make these CAR-Ts widely available.

The Clinical Biomarker Leader / Translational Scientist reports to the Head of Translational Sciences.

Your role

• Critically assess, interpret and present translational data collected during Galapagos’ ongoing clinical trials of all phases
• Co-drive innovation by keeping up-to-date with relevant literature, technology, regulatory guidance and industry developments
• Providing CAR-T biology expertise within the company
• Collaborate with other departments to create synergy in developing biomarker strategies and translational approaches
• Contribute to product characterization and immune monitoring strategy for clinical studies of all phases and across therapeutic areas
• Contribute to study documents, such as IND, Clinical Study Reports and regulatory authority briefing documents

Who are you?

• MD/PhD, PhD or equivalent professional experience in Biomedical / Life Sciences
• 8+ years relevant experience in similar role required
• A deep knowledge and understanding of (CAR) T-cell biology and oncology/hematology
• Demonstrated expertise in immunological methods and profiling of immune cell populations
• Demonstrated experience in designing and implementing biomarker strategies in clinical trials, preferred > phase 2
• Experience with regulatory interactions (FDA/EMA) and briefing book authoring
• Experience with handling and interpretation of large datasets
• Previous experience in industry / biotech
• Ability to be flexible with changing priorities
• Strong collaborative and communicating skills
• Self-driven and can-do mindset, without compromising quality
• Fluent in English

What’s in it for you ?

At Galapagos, we prioritize your continuous growth and development, fostering a culture of empowerment. Our employees are the driving force behind our mission to lead in pharmaceutical research and innovation.

We offer a competitive compensation package and a supportive work environment with strong focus on your health and well-being. Join us in our journey towards sustainability, as we strive to make a lasting impact on both the industry and the planet.

We are Galapagos : together we can make it happen…!